Aliona Golub
Acute leukemia (M3) after liver transplantation
Acute leukemia, specifically Acute Promyelocytic Leukemia (APL), also known as M3 subtype of acute myeloid leukemia (AML), is a rare occurrence after liver transplantation. APL is characterized by the presence of a specific genetic mutation (t(15;17)) that leads to the fusion of the PML and RARA genes. This fusion gene, in turn, produces an abnormal protein that disrupts the normal differentiation of myeloid cells. Developing APL after liver transplantation is unusual, and managing it presents unique challenges due to the patient's immunosuppressed state, potential interactions with the anti-rejection medications they are on, and the complexity of coordinating multiple medical teams...
Panel discussion /All speakers
Panel discussion /All speakers for EET Session 2: Acute myeloid leukemia - Therapies