Chimeric Antigen Receptor T-Cell Therapy in Adult B-Cell Precursor Acute Lymphoblastic Leukaemia: Curative Treatment Option or Bridge to Transplant?

Chimeric Antigen Receptor (CAR) T-cell therapy has demonstrated remarkable efficacy in treating adult patients with relapsed or refractory B-cell precursor Acute Lymphoblastic Leukemia (B-ALL). Its potential to induce deep and sustained remissions has raised important questions about whether CAR T-cell therapy should be considered a curative treatment option or a bridge to hematopoietic stem cell transplantation (HSCT)...